Invest in the power of disruption

The pace of change is greater now than ever before. Disruption is being felt across industries and geographies and proving a differentiator in the long-term performance of investors’ portfolios. There are exciting opportunities but also significant risks for the 'disrupted'.

We believe it is only from a detailed understanding of industries and business models, and through rigorous research, that investors can stay on the right side of change. This content series outlines our managers’ thinking on the key disruptive themes.


What does disruption mean to you?

Evidence of the pace
of disruption

Sequencing the Human Genome

Worldwide Enterprise Spend on 'Digital Transformation'

S&P 500 Technology Sector Earnings

Genetics-based research has accelerated, driven by a dramatic fall in sequencing costs. This has led to the creation of advanced treatment disciplines, such as immuno-oncology, gene therapy and, potentially, personalized vaccines.

Companies globally are investing heavily to keep up with the digital economy.

Tech stocks have soared in recent years. But the performance is backed by impressive earnings growth, highlighting the durability of today's transformation.

Invest in the power of disruption | Janu Henderson Investors
Invest in the power of disruption | Janu Henderson Investors
Invest in the power of disruption | Janu Henderson Investors

Four disruptive themes

Access our manager insight

We believe there are powerful themes shaping, and being shaped by, disruption. Click to read our managers’ latest thinking on each:

Technological disruption

Shifting demographics

A sustainable revolution?

New world order

Technological disruption

The rise of the digital economy is fundamentally changing how all businesses operate. A number of powerful, and investable, trends are linked to this global disruptive force. But which have the strongest potential?

Change is nothing new | Janus Henderson Investors

Change is nothing new

Dec 5, 2018

Businesses such as Amazon and Google are challenging more than just the digital landscape, but is this simply the latest evolution of disruption in markets?

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Keep Up! Technological disruption is accelerating | Janus Henderson Investors

Keep Up! Technological disruption is accelerating

Dec 5, 2018

Converging trends are creating the perfect storm for further disruption in the technology sector. Richard Clode, Global Technology Portfolio Manager, comments on the opportunities that may lie ahead and how to avoid the potential pitfalls that the associated hype may bring.

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China: the next wave of tech disruptors | Janus Henderson Investors

China: the next wave of tech disruptors

Oct 24, 2018

Chinese companies continue to disrupt the technology market. In this video, Richard Clode, Portfolio Manager in the Janus Henderson Global Technology team, discusses his recent trip to China where he met the next wave of disruptors in the sector.

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Global Technology: investing in innovation | Janus Henderson Investors

Global Technology: investing in innovation

Sep 13, 2018

Richard Clode, portfolio manager in the UK-based Janus Henderson Global Technology Team, discusses the concept of innovation, its importance in the team’s investment decisions and where the most attractive opportunities currently are.

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Graeme Clark | Janus Henderson Investors

Global Tech: the importance of navigating the hype cycle

Jul 5, 2018

Graeme Clark, portfolio manager in Janus Henderson’s Global Technology Team, discusses the significance of understanding and analysing where a company sits on the hype cycle when investing in tech for the long term, and how this forms an integral part of the team’s investment process.

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Shifting demographics

New products and changing consumer appetites are widely evident – from millennials to retirees. Drug advances are leading to longer lives and urbanisation continues apace. What does this mean from an investment perspective?

Global Life Sciences: our approach to seeking innovators in cancer therapy | Janus Henderson Investors

Global Life Sciences: our approach to seeking innovators in cancer therapy

April 17, 2018

Follow Global Life Sciences Portfolio Manager Andy Acker and Research Analyst Dan Lyons as they visit biotechnology companies pursuing innovative platforms in which to provide new therapies for major diseases such as cancer.

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A sustainable revolution?

Are we at the tipping point where return on investment is driving companies towards cleaner business practices and green thinking? Which are the most exciting innovations and how can investment help drive, and benefit from, the change?

Sustainability disruption natural twins | Janus Henderson Investors

Sustainability & disruption: natural twins

August 6, 2018

Hamish Chamberlayne, Portfolio Manager of the Global Sustainable Equity Strategy, discusses how these interlinked themes are penetrating every sector of the economy

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New world order

China and other developing markets are growing in different ways to some of the older developed economies. Who will be the beneficiaries of cashless economies, China’s move onto the cloud and higher internet use in emerging markets? And where are the risks?

The only thing that is constant is change | Janus Henderson Investors

‘The only thing that is constant is change’

October 25, 2018

​Disruption is a constant process and any successful investment strategy must take this into account. Andrew Gillan, Head of Asia ex-Japan Equities at Janus Henderson Investors, discusses the opportunities that disruption can offer in the Asia region.

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The Chinese disruption paradox

October 17, 2018

Innovative internet companies are highly disruptive and increasingly dominant within the Chinese economy but they are regulated by the Communist Party, which perceives disruption to be a threat to the status quo. In this video update, Charlie Awdry discusses the interesting implications of this dynamic for investing in China.

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Investing in disruption

Tuesday 25 September, 2:00 pm BST | 30 mins

The world around us is being reshaped by technology as innovative companies disrupt traditional business models and transform the way that individuals lead their lives. In this webcast, Richard Clode, portfolio manager in the Janus Henderson Global Technology Team, will cover:

  • The acceleration and growing breadth of technology disruption
  • Navigating the hype cycle to reduce volatility in technology investing
  • The importance of valuation discipline
  • Performance update and outlook