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Janus Henderson Live: Investing responsibly in the power of AI

At the Janus Henderson Madrid Investment Summit, Michelle Dunstan, Alison Porter, and Dan Lyons explored how AI is reshaping industries - from autonomous vehicles and robotics to healthcare innovation. With applications ranging from cancer detection to surgical training, AI’s complexity underscores the need for active research and responsible engagement.

Michelle Dunstan

Chief Responsibility Officer


Alison Porter

Portfolio Manager


Daniel Lyons, PhD, CFA

Portfolio Manager | Research Analyst


12 Nov 2025
3 minute watch

Key takeaways:

  • From autonomous vehicles and robotics to healthcare innovation and productivity, artificial intelligence (AI) is reshaping how businesses operate and deliver services.
  • AI is already being used to enhance surgical training, detect early-stage cancers, and improve efficiency in healthcare delivery.
  • The complexity and societal impact of AI – such as job displacement and demographic challenges – require thoughtful investment strategies. Janus Henderson emphasises active research and engagement to identify companies using AI responsibly for long-term success.

Generative AI: Refers to deep-learning models that train on large volumes of raw data to generate ‘new content’ including text, images, audio and video.

Hopper chip: Graphics processing unit (GPU) microarchitecture developed by NVIDIA, which introduced powerful AI capabilities excelling in large language models and scientific computing.

Narrator: Janus Henderson live. Madrid investment summit.

Michelle Dunstan: Hi everyone. Today, together with Alison and Dan, we’re going to talk about how to navigate the risks and opportunities in artificial intelligence.

Alison Porter: We have over 5,000 autonomous vehicles in the US already. Dan will talk more on robotics. Amazon Project Vulcan has robots that can actually feel, again that requires additional sensors. It requires machine vision and additional connectivity.

Dunstan: I think people think about economic disruption, but also they’re afraid that the machines are going to steal our jobs. What do you think about that?

Porter: And as a portfolio manager, I’m also a parent with teenage kids. And I think about that a lot and their career progression. And I think it’s really important that we prioritise critical thinking.

I think China has taken this holistic approach to AI training, and part of that is because where they sit in terms of demographics, and that’s why AI really matters, and AI diffusing the demographic timebomb in a number of different ways, from physical productivity of exoskeletons, you know, through to autonomous vehicles that we talked about and healthcare.

Dunstan: We don’t hear as much about healthcare and AI. Should we be hearing about it more?

Dan Lyons: Yeah, that’s a great question, and hopefully I can convince you that there are many examples across health care where AI is being used today, and we’ll see even more examples in the future. The next generation of devices that are in the market today provide training tools that help, you know, maybe a mediocre surgeon learn from the best. How could they do better in procedures and in future iterations of the of the robot, the system will actually intervene and stop the surgeon if they’re about to do something that might have a deleterious outcome for the for the patient.

And it turns out that cancer cells deliver a unique fragment of DNA fragments within the, within the blood and, and in fact, a fingerprint for what could be an early cancer. And companies that have leveraged AI to distil down this really complex problem, to find that needle in a haystack, to better identify it at an early level of cancers. And as a result of that, we already have products on the market that now can screen for 50 different cancer types that before had nothing available.

So healthcare, unfortunately, is a field that’s known a lot for inefficiency. And in these charts here, you’ll see that the US is winning, but it’s actually not a race you want to win. We’re spending the most as a percentage of GDP around the world, but our outcomes are actually fairly middling. In our portfolios at Janus Henderson, we’re trying to find companies that are able to improve the efficiency of delivery of health care.

Dunstan: All of these reasons make AI extremely complex, and that is why we believe you need active research and engagement. Those companies, the ones that are using AI in innovative ways, but with responsibility, are the ones that are going to be prepared to succeed in the long term, and that active research and engagement underpins everything we do at Janus Henderson. It’s that information that gives us better insights to make better investment decisions, and that’s what it means to us to invest in a brighter future together.

Narrator: At Janus Henderson, we are proud to partner with clients to help navigate change. We offer insight, lead investing and innovative solutions to help invest in a brighter future together.

These are the views of the author at the time of publication and may differ from the views of other individuals/teams at Janus Henderson Investors. References made to individual securities do not constitute a recommendation to buy, sell or hold any security, investment strategy or market sector, and should not be assumed to be profitable. Janus Henderson Investors, its affiliated advisor, or its employees, may have a position in the securities mentioned.

 

Past performance does not predict future returns. The value of an investment and the income from it can fall as well as rise and you may not get back the amount originally invested.

 

The information in this article does not qualify as an investment recommendation.

 

There is no guarantee that past trends will continue, or forecasts will be realised.

 

Marketing Communication.

 

Glossary

 

 

 

Michelle Dunstan

Chief Responsibility Officer


Alison Porter

Portfolio Manager


Daniel Lyons, PhD, CFA

Portfolio Manager | Research Analyst


12 Nov 2025
3 minute watch

Key takeaways:

  • From autonomous vehicles and robotics to healthcare innovation and productivity, artificial intelligence (AI) is reshaping how businesses operate and deliver services.
  • AI is already being used to enhance surgical training, detect early-stage cancers, and improve efficiency in healthcare delivery.
  • The complexity and societal impact of AI – such as job displacement and demographic challenges – require thoughtful investment strategies. Janus Henderson emphasises active research and engagement to identify companies using AI responsibly for long-term success.