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Janus Henderson Live: Technology and human resilience in New York

How do artificial intelligence (AI) and bionic enhancements support human resilience in the future? Janus Henderson’s ‘Partnerships for a Brighter Future’ event in New York featured a personal story of recovery as well as insight into the investment potential of technological innovation.

Ali Dibadj

Chief Executive Officer


Richard Clode, CFA

Portfolio Manager


Agustin Mohedas, PhD

Portfolio Manager | Research Analyst


Sarah de Lagarde

Brighter Future Strategist


16 Jul 2025
3 minute watch

Key takeaways:

  • The way technology is harnessed and developed to meet human needs will shape our future. Coupled with human resilience, it is already making the unachievable possible.
  • Innovation will be delivered at a rapid pace in the coming years and has significant benefits in a world of ageing populations and the health challenges this brings.
  • Investment opportunities must be approached in the right way with fundamental analysis essential to see past the stories and identify the winners of tomorrow.

Generative AI: Refers to deep-learning models that train on large volumes of raw data to generate ‘new content’ including text, images, audio and video.

Hopper chip: Graphics processing unit (GPU) microarchitecture developed by NVIDIA, which introduced powerful AI capabilities excelling in large language models and scientific computing.

Janus Henderson Live – partnerships for a brighter future.

Nick Cherney: The future is here. We are living in the future. It’s incredible. And that future is going to continue to be driven not by technology, but by human stories and by human resilience.

Sarah de Lagarde: So, on the 14th of August, 2024, I became the first woman in the world to have climbed Mount Kilimanjaro twice in two years, once able bodied and once disabled with two prosthetics. I’m Sarah de Lagarde and I’m 80% human and 20% bionic.

Richard Clode: There are so many innovations coming down the pipe, and your end game is we have a roadmap that is high conviction, this is going to happen by the end of ’27. You end up with a chip that’s 400 times more powerful than the Hopper chips, and all the models that you’re seeing put out today.

Ali Dibadj: But healthcare, life, life & work and sustainable futures also encompasses this concept of AI, which we’re all thinking about, which we’re all using.

Agustin Mohedas: You know, there’s not enough doctors really to go around. So if we can 10X our radiologists so they can review more films, that’s great. If we can 10X our cardiologists or 10x our nursing staff, these are all huge benefits, especially on the cost side of the equation.

And because of the ageing population, healthcare costs are only going to continue to balloon, you know, because we are surviving cancer, surviving heart attacks, but we’re going to get neurodegenerative diseases. Almost surely we are going to need people to take care of us in those conditions. And so we’re going to need these robots to really kind of be successful.

De Lagarde: Every time that I use the arm, data gets collected and stored on an external server, and an AI machine learning algorithm sifts through those data sets and starts recognising patterns. And once there is sufficient data to play with, the algorithm swaps over to become generative AI, and it starts predicting what my next move is going to be.

Mohedas: Yes, these technologies are exciting, and they’re going to proliferate. We still got to get down to fundamentals and picking, you know, the right opportunities and the right companies that are making the most and taking the most advantage of these technologies, not just kind of selling a story.

Clode: So I think that’s a huge investment opportunity. As Sarah was saying, we’re talking about trillions of dollars of spend here that could be given in the form of either software or physical robot and robotics. That’s an incredible investment opportunity in the next few years. You know, we always think of technology, as the science of solving problems, the bigger the problem, the bigger the addressable market and the bigger the potential stock returns you’re going to get out of that.

At Janus Henderson, we are proud to partner together with clients to help navigate change. We offer insight-led investing and innovative solutions to help invest in a brighter future together.

These are the views of the author at the time of publication and may differ from the views of other individuals/teams at Janus Henderson Investors. References made to individual securities do not constitute a recommendation to buy, sell or hold any security, investment strategy or market sector, and should not be assumed to be profitable. Janus Henderson Investors, its affiliated advisor, or its employees, may have a position in the securities mentioned.

 

Past performance does not predict future returns. The value of an investment and the income from it can fall as well as rise and you may not get back the amount originally invested.

 

The information in this article does not qualify as an investment recommendation.

 

There is no guarantee that past trends will continue, or forecasts will be realised.

 

Marketing Communication.

 

Glossary

 

 

 

Important information

Please read the following important information regarding funds related to this article.

The Janus Henderson Horizon Fund (the “Fund”) is a Luxembourg SICAV incorporated on 30 May 1985, managed by Janus Henderson Investors Europe S.A. Janus Henderson Investors Europe S.A. may decide to terminate the marketing arrangements of this Collective Investment Scheme in accordance with the appropriate regulation. This is a marketing communication. Please refer to the prospectus of the UCITS and to the KIID before making any final investment decisions.
    Specific risks
  • Shares/Units can lose value rapidly, and typically involve higher risks than bonds or money market instruments. The value of your investment may fall as a result.
  • Shares of small and mid-size companies can be more volatile than shares of larger companies, and at times it may be difficult to value or to sell shares at desired times and prices, increasing the risk of losses.
  • If a Fund has a high exposure to a particular country or geographical region it carries a higher level of risk than a Fund which is more broadly diversified.
  • The Fund is focused towards particular industries or investment themes and may be heavily impacted by factors such as changes in government regulation, increased price competition, technological advancements and other adverse events.
  • The Fund follows a sustainable investment approach, which may cause it to be overweight and/or underweight in certain sectors and thus perform differently than funds that have a similar objective but which do not integrate sustainable investment criteria when selecting securities.
  • The Fund may use derivatives with the aim of reducing risk or managing the portfolio more efficiently. However this introduces other risks, in particular, that a derivative counterparty may not meet its contractual obligations.
  • If the Fund holds assets in currencies other than the base currency of the Fund, or you invest in a share/unit class of a different currency to the Fund (unless hedged, i.e. mitigated by taking an offsetting position in a related security), the value of your investment may be impacted by changes in exchange rates.
  • When the Fund, or a share/unit class, seeks to mitigate exchange rate movements of a currency relative to the base currency (hedge), the hedging strategy itself may positively or negatively impact the value of the Fund due to differences in short-term interest rates between the currencies.
  • Securities within the Fund could become hard to value or to sell at a desired time and price, especially in extreme market conditions when asset prices may be falling, increasing the risk of investment losses.
  • The Fund could lose money if a counterparty with which the Fund trades becomes unwilling or unable to meet its obligations, or as a result of failure or delay in operational processes or the failure of a third party provider.
The Janus Henderson Horizon Fund (the “Fund”) is a Luxembourg SICAV incorporated on 30 May 1985, managed by Janus Henderson Investors Europe S.A. Janus Henderson Investors Europe S.A. may decide to terminate the marketing arrangements of this Collective Investment Scheme in accordance with the appropriate regulation. This is a marketing communication. Please refer to the prospectus of the UCITS and to the KIID before making any final investment decisions.
    Specific risks
  • Shares/Units can lose value rapidly, and typically involve higher risks than bonds or money market instruments. The value of your investment may fall as a result.
  • If a Fund has a high exposure to a particular country or geographical region it carries a higher level of risk than a Fund which is more broadly diversified.
  • The Fund is focused towards particular industries or investment themes and may be heavily impacted by factors such as changes in government regulation, increased price competition, technological advancements and other adverse events.
  • This Fund may have a particularly concentrated portfolio relative to its investment universe or other funds in its sector. An adverse event impacting even a small number of holdings could create significant volatility or losses for the Fund.
  • The Fund may use derivatives with the aim of reducing risk or managing the portfolio more efficiently. However this introduces other risks, in particular, that a derivative counterparty may not meet its contractual obligations.
  • If the Fund holds assets in currencies other than the base currency of the Fund, or you invest in a share/unit class of a different currency to the Fund (unless hedged, i.e. mitigated by taking an offsetting position in a related security), the value of your investment may be impacted by changes in exchange rates.
  • When the Fund, or a share/unit class, seeks to mitigate exchange rate movements of a currency relative to the base currency (hedge), the hedging strategy itself may positively or negatively impact the value of the Fund due to differences in short-term interest rates between the currencies.
  • Securities within the Fund could become hard to value or to sell at a desired time and price, especially in extreme market conditions when asset prices may be falling, increasing the risk of investment losses.
  • The Fund could lose money if a counterparty with which the Fund trades becomes unwilling or unable to meet its obligations, or as a result of failure or delay in operational processes or the failure of a third party provider.
Janus Henderson Capital Funds Plc is a UCITS established under Irish law, with segregated liability between funds. Investors are warned that they should only make their investments based on the most recent Prospectus which contains information about fees, expenses and risks, which is available from all distributors and paying/facilities agents, it should be read carefully. This is a marketing communication. Please refer to the prospectus of the UCITS and to the KIID before making any final investment decisions. The rate of return may vary and the principal value of an investment will fluctuate due to market and foreign exchange movements. Shares, if redeemed, may be worth more or less than their original cost. This is not a solicitation for the sale of shares and nothing herein is intended to amount to investment advice. Janus Henderson Investors Europe S.A. may decide to terminate the marketing arrangements of this Collective Investment Scheme in accordance with the appropriate regulation.
    Specific risks
  • Shares/Units can lose value rapidly, and typically involve higher risks than bonds or money market instruments. The value of your investment may fall as a result.
  • Shares of small and mid-size companies can be more volatile than shares of larger companies, and at times it may be difficult to value or to sell shares at desired times and prices, increasing the risk of losses.
  • If a Fund has a high exposure to a particular country or geographical region it carries a higher level of risk than a Fund which is more broadly diversified.
  • The Fund is focused towards particular industries or investment themes and may be heavily impacted by factors such as changes in government regulation, increased price competition, technological advancements and other adverse events.
  • The Fund may use derivatives to help achieve its investment objective. This can result in leverage (higher levels of debt), which can magnify an investment outcome. Gains or losses to the Fund may therefore be greater than the cost of the derivative. Derivatives also introduce other risks, in particular, that a derivative counterparty may not meet its contractual obligations.
  • If the Fund holds assets in currencies other than the base currency of the Fund, or you invest in a share/unit class of a different currency to the Fund (unless hedged, i.e. mitigated by taking an offsetting position in a related security), the value of your investment may be impacted by changes in exchange rates.
  • When the Fund, or a share/unit class, seeks to mitigate exchange rate movements of a currency relative to the base currency (hedge), the hedging strategy itself may positively or negatively impact the value of the Fund due to differences in short-term interest rates between the currencies.
  • Securities within the Fund could become hard to value or to sell at a desired time and price, especially in extreme market conditions when asset prices may be falling, increasing the risk of investment losses.
  • The Fund could lose money if a counterparty with which the Fund trades becomes unwilling or unable to meet its obligations, or as a result of failure or delay in operational processes or the failure of a third party provider.
The Janus Henderson Horizon Fund (the “Fund”) is a Luxembourg SICAV incorporated on 30 May 1985, managed by Janus Henderson Investors Europe S.A. Janus Henderson Investors Europe S.A. may decide to terminate the marketing arrangements of this Collective Investment Scheme in accordance with the appropriate regulation. This is a marketing communication. Please refer to the prospectus of the UCITS and to the KIID before making any final investment decisions.
    Specific risks
  • Shares/Units can lose value rapidly, and typically involve higher risks than bonds or money market instruments. The value of your investment may fall as a result.
  • Shares of small and mid-size companies can be more volatile than shares of larger companies, and at times it may be difficult to value or to sell shares at desired times and prices, increasing the risk of losses.
  • If a Fund has a high exposure to a particular country or geographical region it carries a higher level of risk than a Fund which is more broadly diversified.
  • The Fund is focused towards particular industries or investment themes and may be heavily impacted by factors such as changes in government regulation, increased price competition, technological advancements and other adverse events.
  • The Fund may use derivatives to help achieve its investment objective. This can result in leverage (higher levels of debt), which can magnify an investment outcome. Gains or losses to the Fund may therefore be greater than the cost of the derivative. Derivatives also introduce other risks, in particular, that a derivative counterparty may not meet its contractual obligations.
  • If the Fund holds assets in currencies other than the base currency of the Fund, or you invest in a share/unit class of a different currency to the Fund (unless hedged, i.e. mitigated by taking an offsetting position in a related security), the value of your investment may be impacted by changes in exchange rates.
  • When the Fund, or a share/unit class, seeks to mitigate exchange rate movements of a currency relative to the base currency (hedge), the hedging strategy itself may positively or negatively impact the value of the Fund due to differences in short-term interest rates between the currencies.
  • Securities within the Fund could become hard to value or to sell at a desired time and price, especially in extreme market conditions when asset prices may be falling, increasing the risk of investment losses.
  • The Fund may incur a higher level of transaction costs as a result of investing in less actively traded or less developed markets compared to a fund that invests in more active/developed markets.
  • The Fund could lose money if a counterparty with which the Fund trades becomes unwilling or unable to meet its obligations, or as a result of failure or delay in operational processes or the failure of a third party provider.
Ali Dibadj

Chief Executive Officer


Richard Clode, CFA

Portfolio Manager


Agustin Mohedas, PhD

Portfolio Manager | Research Analyst


Sarah de Lagarde

Brighter Future Strategist


16 Jul 2025
3 minute watch

Key takeaways:

  • The way technology is harnessed and developed to meet human needs will shape our future. Coupled with human resilience, it is already making the unachievable possible.
  • Innovation will be delivered at a rapid pace in the coming years and has significant benefits in a world of ageing populations and the health challenges this brings.
  • Investment opportunities must be approached in the right way with fundamental analysis essential to see past the stories and identify the winners of tomorrow.