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Chart to Watch: Biopharma dealmaking gains momentum

After a notable pickup toward the end of last year, biopharma M&A and IPO activity have accelerated in 2026. Portfolio Manager Andy Acker discusses how the increase in deal activity mirrors the pace of innovation taking place across biotechnology and its potential implications for the broader healthcare sector.

Chart to Watch: Biopharma dealmaking gains momentum

Source: Bloomberg, as of 30 June 2026. Represents global M&A transactions where the target industry is classified as Biotech & Pharma.

What excites us most isn't necessarily the increase in deal activity, but what it says about innovation across the biotech landscape. We continue to see a broad wave of scientific advances taking shape in areas such as oncology, immunology, rare diseases, and other fields with significant unmet medical need. The pickup in M&A and capital markets activity suggests strategic acquirers and investors increasingly recognize the value of these innovations and their potential to improve patient outcomes.

Andy Acker, Portfolio Manager

Key takeaways

  • Despite a higher interest-rate backdrop than many expected at the start of the year, the momentum we saw building in biotech deal activity has continued unabated, with both the dollar value and breadth of transactions inflecting higher during the first half of 2026.
  • The continued pace of acquisitions highlights biotechnology's important role in driving healthcare innovation. Notably, many deals have targeted small- and mid-cap biotech companies advancing promising clinical programs, an area where we continue to find attractive investment opportunities. With large pharmaceuticals under pressure to replace hundreds of billions of dollars in drug revenues that will lose patent protection in the coming years, we believe demand for differentiated biotech assets should remain strong.
  • Beyond M&A, biotech initial public offering (IPO) activity has rebounded, including two of the largest biotech IPOs on record during the second quarter. A healthier funding environment can benefit the broader biopharmaceutical ecosystem, helping support the discovery and development of future medicines while creating opportunities for companies providing the tools and services that enable innovation.
Aug 17, 2026
1 minute read

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