Please ensure Javascript is enabled for purposes of website accessibility Global Life Sciences Fund - Janus Henderson Investors
For Institutional Investors in the US

Global Life Sciences Fund Holdings

Full Portfolio Holdings

(As of February 29, 2024)

% OF INVESTMENTS
Eli Lilly & Co 6.63
UnitedHealth Group Inc 5.96
Novo Nordisk A/S 4.80
Merck & Co Inc 3.55
AstraZeneca PLC 3.55
AbbVie Inc 3.22
Abbott Laboratories 2.49
Sanofi SA 2.46
Vertex Pharmaceuticals Inc 2.38
Boston Scientific Corp 2.29
Novartis AG (ADR) 2.18
Amgen Inc 2.09
Thermo Fisher Scientific Inc 2.06
Danaher Corp 1.88
Sarepta Therapeutics Inc 1.88
Stryker Corp 1.68
Cencora Inc 1.62
Elevance Health Inc 1.62
Argenx SE (ADR) 1.54
Intuitive Surgical Inc 1.44
Ascendis Pharma A/S (ADR) 1.43
Madrigal Pharmaceuticals Inc 1.40
Vaxcyte Inc 1.31
Roche Holding AG 1.31
HCA Healthcare Inc 1.26
Edwards Lifesciences Corp 1.21
Humana Inc 1.11
Biohaven Ltd 1.04
Zoetis Inc 1.00
Neurocrine Biosciences Inc 0.96
Centene Corp 0.91
Globus Medical Inc 0.91
Cymabay Therapeutics Inc 0.91
Akero Therapeutics Inc 0.89
Ardelyx Inc 0.85
United Therapeutics Corp 0.85
Lantheus Holdings Inc 0.82
Johnson & Johnson 0.75
Hoya Corp 0.73
Teleflex Inc 0.72
Avadel Pharmaceuticals PLC (ADR) 0.71
STERIS PLC 0.70
Regeneron Pharmaceuticals Inc 0.69
Cooper Cos Inc 0.69
Medtronic PLC 0.69
Illumina Inc 0.68
89bio Inc 0.64
Legend Biotech Corp (ADR) 0.64
Zai Lab Ltd (ADR) 0.62
Ideaya Biosciences Inc 0.61
Arcellx Inc 0.61
PTC Therapeutics Inc 0.59
Astellas Pharma Inc 0.56
4D Molecular Therapeutics Inc 0.56
Amicus Therapeutics Inc 0.56
Catalent Inc 0.50
ICON PLC 0.50
Janux Therapeutics Inc 0.50
DexCom Inc 0.50
BioMarin Pharmaceutical Inc 0.48
Penumbra Inc 0.48
Cytokinetics Inc 0.48
Soleno Therapeutics Inc 0.47
Royalty Pharma plc 0.46
Align Technology Inc 0.41
Shockwave Medical Inc 0.40
Baxter International Inc 0.39
Sotera Health Co 0.39
Gilead Sciences Inc 0.39
REVOLUTION Medicines Inc 0.38
New Horizon Health Ltd 0.38
Takeda Pharmaceutical Co Ltd 0.36
DENTSPLY SIRONA Inc 0.34
Alnylam Pharmaceuticals Inc 0.31
Mirum Pharmaceuticals Inc 0.31
Tandem Diabetes Care Inc 0.30
Prothena Corp PLC 0.30
Structure Therapeutics Inc (ADR) 0.29
IQVIA Holdings Inc 0.28
NeoGenomics Inc 0.28
CG oncology Inc 0.26
Cargo Therapeutics Inc 0.26
Rhythm Pharmaceuticals Inc 0.24
Bridgebio Pharma Inc 0.23
Xenon Pharmaceuticals Inc 0.22
Intra-Cellular Therapies Inc 0.21
Insmed Inc 0.21
Collegium Pharmaceutical Inc 0.21
Catalyst Pharmaceuticals Inc 0.21
Immunome Inc 0.20
Biomea Fusion Inc 0.19
Disc Medicine Inc 0.17
Element Biosciences Inc 0.13
Rocket Pharmaceuticals Inc 0.12
Synthekine Inc 0.11
Bicara Therapeutics Inc 0.11
Heartflow Inc 0.11
Attralus Inc 0.10
Curevo Inc 0.10
Lexeo Therapeutics Inc 0.10
Shoreline Biosciences Inc 0.09
Lexeo Therapeutics Inc 0.09
Neurogene Inc 0.08
Sonoma Biotherapeutics Inc 0.08
Neurogene Inc 0.07
Neurogene Inc 0.07
Magnolia Medical Technologies Inc 0.06
Freenome Holdings Inc 0.05
Freenome Holdings Inc 0.05
Sonoma Biotherapeutics Inc 0.04
Asher Biotherapeutics Inc 0.04
Arbor Biotechnologies Inc 0.03
Hemoshear Therapeutics LLC 0.03
Lexeo Therapeutics Inc 0.03
Twinstrand Biosciences Inc 0.03
Hemoshear Therapeutics LLC, 10.00%, 05/01/24 0.01
Hemoshear Therapeutics LLC, 10.00%, 12/31/25 0.00
Leap Therapeutics Inc 0.00
Clementia Pharmaceuticals Inc 0.00
Cash & Equivalents 0.54
Janus Henderson publishes this listing of securities held as of the most recently available disclosure period, which varies depending on the portfolio. Any portion of holdings may be excluded from publication when deemed in the best interest of the portfolio. Securities are reported at market value.
The portfolio data and its presentation here is based on the investment book of record and may differ from the accounting book of record and complete schedules of investments in regulatory filings due to differing accounting and reporting standards.