Global Life Sciences Fund Holdings

Full Portfolio Holdings

(As of August 31, 2020)

% OF INVESTMENTS
Merck & Co Inc 3.81
UnitedHealth Group Inc 3.50
Novartis AG (ADR) 3.37
AbbVie Inc 3.20
Roche Holding AG 3.08
Thermo Fisher Scientific Inc 3.06
AstraZeneca PLC 2.94
Abbott Laboratories 2.65
Boston Scientific Corp 2.60
Humana Inc 2.54
Bristol-Myers Squibb Co 2.23
Sanofi 2.22
Eli Lilly and Co 1.90
Danaher Corp 1.86
Neurocrine Biosciences Inc 1.84
Medtronic PLC 1.79
Horizon Therapeutics Plc 1.71
Johnson & Johnson 1.68
Vertex Pharmaceuticals Inc 1.63
Elanco Animal Health Inc 1.62
Gilead Sciences Inc 1.56
Ascendis Pharma A/S (ADR) 1.46
Sarepta Therapeutics Inc 1.45
Centene Corp 1.38
Catalent Inc 1.37
IQVIA Holdings Inc 1.30
Mirati Therapeutics Inc 1.16
Anthem Inc 1.15
Takeda Pharmaceutical Co Ltd 1.11
Novo Nordisk A/S 1.09
Insmed Inc 1.08
Royalty Pharma Finance Trust 1.07
Global Blood Therapeutics Inc 1.06
BioMarin Pharmaceutical Inc 1.03
Baxter International Inc 0.98
Jazz Pharmaceuticals PLC 0.98
GW Pharmaceuticals PLC (ADR) 0.97
ACADIA Pharmaceuticals Inc 0.94
Rhythm Pharmaceuticals Inc 0.87
Amicus Therapeutics Inc 0.84
Intuitive Surgical Inc 0.84
Edwards Lifesciences Corp 0.83
Alexion Pharmaceuticals Inc 0.79
Globus Medical Inc 0.77
Akero Therapeutics Inc 0.76
Quest Diagnostics Inc 0.76
Cooper Cos Inc 0.74
ICU Medical Inc 0.71
Regeneron Pharmaceuticals Inc 0.71
Sage Therapeutics Inc 0.68
Stryker Corp 0.67
STERIS PLC 0.63
Acceleron Pharma Inc 0.62
Silk Road Medical Inc 0.59
PTC Therapeutics Inc 0.59
DENTSPLY SIRONA Inc 0.56
Bayer AG 0.56
Teleflex Inc 0.56
Astellas Pharma Inc 0.54
Myovant Sciences Ltd 0.52
Exelixis Inc 0.52
DexCom Inc 0.51
Forma Therapeutics Holdings Inc 0.51
Argenx SE (ADR) 0.51
Retrophin Inc 0.50
Lonza Group AG 0.49
iTeos Therapeutics SA 0.49
NeoGenomics Inc 0.49
Fate Therapeutics Inc 0.47
Bristol-Myers Squibb Co 0.45
ALX Oncology Inc 0.45
Collegium Pharmaceutical Inc 0.42
Immunomedics Inc 0.41
Acerta Project Management Co 0.41
Phathom Pharmaceuticals Inc 0.40
FibroGen Inc 0.39
Vaxcyte Inc 0.39
Bridgebio Pharma Inc 0.37
Zogenix Inc 0.36
Health Catalyst Inc 0.35
Odonate Therapeutics Inc 0.35
IGM Biosciences Inc 0.34
Axsome Therapeutics Inc 0.34
Ironwood Pharmaceuticals Inc 0.31
Seres Therapeutics Inc 0.29
iTeos Therapeutics Inc 0.25
Annexon Inc 0.24
Kiniksa Pharmaceuticals Ltd 0.23
BioNTech SE (ADR) 0.23
Bigfoot Biomedical Inc 0.22
Vaxcyte Inc 0.21
Aprea Therapeutics Inc 0.21
Kymera Therapeutics LLC 0.21
Harmony Biosciences Holdings Inc 0.21
Annexon Inc 0.19
4d Molecular Therapeutics LLC 0.15
Everest Medicines US Ltd 0.14
Takeda Pharmaceutical Co Ltd 0.14
ALX Oncology Holdings Inc 0.14
Olema Pharmaceuticals Inc 0.12
VelosBio Inc 0.11
Aligos Therapeutics Inc 0.08
C4 Therapeutics Inc 0.07
BioAtla LLC 0.06
Kinnate Biopharma Inc 0.06
Freenome Inc 0.05
Bigfoot Biomedical Inc 0.04
Clementia Pharmaceuticals Inc 0.00
Cash & Equivalents 0.61
Holdings are subject to change without notice.

Janus Henderson publishes this listing of securities held as of the most recently available disclosure period, which varies depending on the portfolio. Any portion of holdings may be excluded from publication when deemed in the best interest of the portfolio.

 

Securities are reported at market value.

The portfolio data and its presentation here may differ from the complete schedules of investments in regulatory filings due to differing accounting and reporting requirements.
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