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Global Life Sciences Diversified ADR Managed Account Holdings

Full Portfolio Holdings

(As of 03/31/2025)

% OF INVESTMENTS
Eli Lilly & Co 9.50
UnitedHealth Group Inc 6.92
AstraZeneca PLC (ADR) 4.01
Johnson & Johnson 3.53
Boston Scientific Corp 3.13
Sanofi SA (ADR) 3.11
Abbott Laboratories 3.09
Amgen Inc 2.95
AbbVie Inc 2.89
Vertex Pharmaceuticals Inc 2.79
Novo Nordisk A/S (ADR) 2.43
Novartis AG (ADR) 2.37
Thermo Fisher Scientific Inc 2.29
Argenx SE (ADR) 2.04
Intuitive Surgical Inc 1.99
Merck & Co Inc 1.78
Danaher Corp 1.77
Stryker Corp 1.71
Medtronic PLC 1.50
Roche Holding AG (ADR) 1.47
Ascendis Pharma A/S (ADR) 1.43
Soleno Therapeutics Inc 1.42
Akero Therapeutics Inc 1.40
HCA Healthcare Inc 1.39
McKesson Corp 1.35
Madrigal Pharmaceuticals Inc 1.33
Cencora Inc 1.20
Globus Medical Inc 1.05
Lantheus Holdings Inc 1.04
Verona Pharma PLC (ADR) 1.00
Avidity Biosciences Inc 1.00
Elevance Health Inc 1.00
REVOLUTION Medicines Inc 0.93
CVS Health Corp 0.88
DexCom Inc 0.80
Teva Pharmaceutical Industries Ltd (ADR) 0.76
Bridgebio Pharma Inc 0.74
Mirum Pharmaceuticals Inc 0.71
Zoetis Inc 0.71
Penumbra Inc 0.69
Zai Lab Ltd (ADR) 0.63
Edwards Lifesciences Corp 0.62
Vaxcyte Inc 0.62
PTC Therapeutics Inc 0.60
Sarepta Therapeutics Inc 0.59
Gilead Sciences Inc 0.58
Cooper Cos Inc 0.56
Inspire Medical Systems Inc 0.55
Humana Inc 0.53
Centene Corp 0.51
Biohaven Ltd 0.48
89bio Inc 0.48
Alnylam Pharmaceuticals Inc 0.47
Travere Therapeutics Inc 0.46
Align Technology Inc 0.46
STERIS PLC 0.46
Ardelyx Inc 0.44
Avadel Pharmaceuticals PLC 0.42
Dyne Therapeutics Inc 0.40
Teleflex Inc 0.40
Arcellx Inc 0.40
Edgewise Therapeutics Inc 0.34
Legend Biotech Corp (ADR) 0.33
Insmed Inc 0.33
Janux Therapeutics Inc 0.32
Sotera Health Co 0.29
Ideaya Biosciences Inc 0.29
Neurocrine Biosciences Inc 0.29
Amicus Therapeutics Inc 0.27
Crinetics Pharmaceuticals Inc 0.27
United Therapeutics Corp 0.27
Nuvalent Inc 0.26
Cytokinetics Inc 0.25
IQVIA Holdings Inc 0.25
ICON PLC 0.25
Structure Therapeutics Inc (ADR) 0.25
Xenon Pharmaceuticals Inc 0.21
Apogee Therapeutics Inc 0.18
Illumina Inc 0.18
NeoGenomics Inc 0.18
Bicara Therapeutics Inc 0.16
CG oncology Inc 0.15
Praxis Precision Medicines Inc 0.14
Beam Therapeutics Inc 0.13
Immunome Inc 0.13
Geron Corp 0.11
Rocket Pharmaceuticals Inc 0.10
Cash & Equivalents 1.31
Janus Henderson publishes this listing of securities held as of the most recently available disclosure period, which varies depending on the portfolio. Any portion of holdings may be excluded from publication when deemed in the best interest of the portfolio. Securities are reported at market value.