Please ensure Javascript is enabled for purposes of website accessibility Global Life Sciences Fund - Janus Henderson Investors - US Advisor
For Financial Professionals in the US

Global Life Sciences Fund Holdings

Full Portfolio Holdings

(As of 03/31/2025)

% OF INVESTMENTS
Eli Lilly & Co 9.40
UnitedHealth Group Inc 6.88
AstraZeneca PLC 4.01
Johnson & Johnson 3.59
Boston Scientific Corp 3.13
Abbott Laboratories 3.09
Sanofi SA 3.06
Amgen Inc 2.90
AbbVie Inc 2.83
Vertex Pharmaceuticals Inc 2.82
Novo Nordisk A/S 2.40
Thermo Fisher Scientific Inc 2.36
Novartis AG (ADR) 2.34
Argenx SE (ADR) 2.13
Intuitive Surgical Inc 1.88
Stryker Corp 1.79
Danaher Corp 1.79
Merck & Co Inc 1.75
Medtronic PLC 1.52
Roche Holding AG 1.50
Ascendis Pharma A/S (ADR) 1.44
Soleno Therapeutics Inc 1.40
McKesson Corp 1.34
Akero Therapeutics Inc 1.34
HCA Healthcare Inc 1.34
Madrigal Pharmaceuticals Inc 1.31
Cencora Inc 1.16
Globus Medical Inc 1.06
Avidity Biosciences Inc 1.05
Lantheus Holdings Inc 1.04
Verona Pharma PLC (ADR) 1.03
Elevance Health Inc 0.99
REVOLUTION Medicines Inc 0.93
CVS Health Corp 0.84
DexCom Inc 0.81
Teva Pharmaceutical Industries Ltd (ADR) 0.77
Bridgebio Pharma Inc 0.77
Zoetis Inc 0.71
Vaxcyte Inc 0.70
Mirum Pharmaceuticals Inc 0.68
Penumbra Inc 0.68
Edwards Lifesciences Corp 0.63
Zai Lab Ltd (ADR) 0.61
Gilead Sciences Inc 0.59
Sarepta Therapeutics Inc 0.58
Cooper Cos Inc 0.55
Inspire Medical Systems Inc 0.55
PTC Therapeutics Inc 0.53
Centene Corp 0.49
Biohaven Ltd 0.48
Travere Therapeutics Inc 0.48
Humana Inc 0.48
89bio Inc 0.46
Ardelyx Inc 0.43
Align Technology Inc 0.43
STERIS PLC 0.42
Avadel Pharmaceuticals PLC 0.41
Dyne Therapeutics Inc 0.39
Teleflex Inc 0.39
Arcellx Inc 0.38
Alnylam Pharmaceuticals Inc 0.37
Insmed Inc 0.34
Legend Biotech Corp (ADR) 0.33
Edgewise Therapeutics Inc 0.32
United Therapeutics Corp 0.30
Janux Therapeutics Inc 0.30
Neurocrine Biosciences Inc 0.30
Sotera Health Co 0.29
Nuvalent Inc 0.29
Rhythm Pharmaceuticals Inc 0.28
Ideaya Biosciences Inc 0.28
ICON PLC 0.26
Xenon Pharmaceuticals Inc 0.24
Crinetics Pharmaceuticals Inc 0.24
Amicus Therapeutics Inc 0.23
Apogee Therapeutics Inc 0.22
Structure Therapeutics Inc (ADR) 0.22
Cytokinetics Inc 0.21
Hoya Corp 0.20
Illumina Inc 0.19
IQVIA Holdings Inc 0.17
Metsera Inc 0.17
NeoGenomics Inc 0.16
CG oncology Inc 0.15
Praxis Precision Medicines Inc 0.14
Beam Therapeutics Inc 0.13
Heartflow Inc 0.13
Bicara Therapeutics Inc 0.12
Immunome Inc 0.12
Curevo Inc 0.11
Geron Corp 0.09
Attralus Inc 0.08
Rocket Pharmaceuticals Inc 0.08
Element Biosciences Inc 0.07
Magnolia Medical Technologies Inc 0.07
4D Molecular Therapeutics Inc 0.07
Asher Biotherapeutics Inc 0.06
Shoreline Biosciences Inc 0.06
Green Cross Holdings Corp 0.05
Lexeo Therapeutics Inc 0.05
HeartFlow Inc, 0.00%, 12/02/24 0.04
Sonoma Biotherapeutics Inc 0.04
Freenome Holdings Inc 0.04
Freenome Holdings Inc 0.04
Loadsmart Inc 0.04
Asher Biotherapeutics Inc 0.03
Twinstrand Biosciences Inc 0.03
Sonoma Biotherapeutics Inc 0.02
Bicara Therapeutics Inc 0.01
Hemoshear Therapeutics LLC 0.01
Magnolia Medical Technologies 0.00
Clementia Pharmaceuticals Inc 0.00
Cash & Equivalents 0.37
Janus Henderson publishes this listing of securities held as of the most recently available disclosure period, which varies depending on the portfolio. Any portion of holdings may be excluded from publication when deemed in the best interest of the portfolio. Securities are reported at market value.
The portfolio data and its presentation here is based on the investment book of record and may differ from the accounting book of record and complete schedules of investments in regulatory filings due to differing accounting and reporting standards.