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Global Life Sciences Fund Holdings

Full Portfolio Holdings

(As of 02/28/2026)

% OF INVESTMENTS
Eli Lilly & Co 9.36
Johnson & Johnson 6.92
AstraZeneca PLC 4.61
AbbVie Inc 3.83
UnitedHealth Group Inc 3.11
Novartis AG (ADR) 2.94
Abbott Laboratories 2.53
Roche Holding AG 2.49
Praxis Precision Medicines Inc 2.39
Argenx SE (ADR) 2.35
Thermo Fisher Scientific Inc 2.28
Vertex Pharmaceuticals Inc 2.16
Boston Scientific Corp 2.08
Intuitive Surgical Inc 2.07
HCA Healthcare Inc 2.02
REVOLUTION Medicines Inc 2.00
Sanofi SA 1.98
Amgen Inc 1.89
Stryker Corp 1.82
Bridgebio Pharma Inc 1.79
Ascendis Pharma A/S (ADR) 1.59
Danaher Corp 1.58
CVS Health Corp 1.54
McKesson Corp 1.47
Globus Medical Inc 1.29
Gilead Sciences Inc 1.29
Merck & Co Inc 1.29
Teva Pharmaceutical Industries Ltd (ADR) 1.24
PTC Therapeutics Inc 1.23
Mirum Pharmaceuticals Inc 1.14
Madrigal Pharmaceuticals Inc 1.13
Elevance Health Inc 1.11
Vaxcyte Inc 1.08
United Therapeutics Corp 1.06
Cencora Inc 1.04
Medtronic PLC 1.03
Travere Therapeutics Inc 0.77
Medline Inc 0.74
Edwards Lifesciences Corp 0.71
Dyne Therapeutics Inc 0.71
Lantheus Holdings Inc 0.70
Soleno Therapeutics Inc 0.70
DexCom Inc 0.69
Structure Therapeutics Inc (ADR) 0.65
Penumbra Inc 0.60
Becton Dickinson & Co 0.58
UCB SA 0.56
Glaukos Corp 0.53
Cooper Cos Inc 0.49
Apogee Therapeutics Inc 0.48
Biohaven Ltd 0.46
Ideaya Biosciences Inc 0.44
Tarsus Pharmaceuticals Inc 0.38
STERIS PLC 0.37
Daiichi Sankyo Co Ltd 0.37
Cogent Biosciences Inc 0.35
Edgewise Therapeutics Inc 0.35
Regeneron Pharmaceuticals Inc 0.34
Neurocrine Biosciences Inc 0.33
Ardelyx Inc 0.31
Zoetis Inc 0.31
Sotera Health Co 0.31
Crinetics Pharmaceuticals Inc 0.29
Olema Pharmaceuticals Inc 0.29
Heartflow Inc 0.28
Alnylam Pharmaceuticals Inc 0.28
Centene Corp 0.28
Scholar Rock Holding Corp 0.27
Rhythm Pharmaceuticals Inc 0.27
Protagonist Therapeutics Inc 0.27
Insulet Corp 0.26
Terns Pharmaceuticals Inc 0.25
Illumina Inc 0.25
Xenon Pharmaceuticals Inc 0.24
Nuvalent Inc 0.24
KARDIUM SERIES 8 CLASS D PREFERRED SHARES USD 0.22
Teleflex Inc 0.22
Mirum Pharmaceuticals Inc 0.21
Humana Inc 0.18
Janux Therapeutics Inc 0.18
4D Molecular Therapeutics Inc 0.15
Avidity Biosciences Inc 0.15
Immunome Inc 0.15
Curevo Inc 0.10
Lexeo Therapeutics Inc 0.08
Loadsmart Inc 0.06
KARDIUM SERIES 8 CLASS D PREFERRED SHARES USD 0.06
Magnolia Medical Technologies Inc 0.05
Element Biosciences Inc 0.04
Green Cross Holdings Corp 0.04
Sonoma Biotherapeutics Inc 0.04
PFIZER INC 0.03
Twinstrand Biosciences Inc 0.02
Sonoma Biotherapeutics Inc 0.02
Freenome Holdings Inc 0.02
Freenome Holdings Inc 0.02
Asher Biotherapeutics Inc 0.01
Attralus Inc 0.01
Asher Biotherapeutics Inc 0.01
Novo Nordisk A/S 0.01
Hemoshear Therapeutics LLC 0.01
Heartflow Inc 0.01
Alkermes PLC 0.01
Atrium Therapeutics Inc 0.00
Cash & Equivalents 0.46
Janus Henderson publishes this listing of securities held as of the most recently available disclosure period, which varies depending on the portfolio. Any portion of holdings may be excluded from publication when deemed in the best interest of the portfolio. Securities are reported at market value.
The portfolio data and its presentation here is based on the investment book of record and may differ from the accounting book of record and complete schedules of investments in regulatory filings due to differing accounting and reporting standards.