For Financial Professionals in the US

Global Life Sciences Fund Holdings

Full Portfolio Holdings

(As of 07/31/2023)

% OF INVESTMENTS
UnitedHealth Group Inc 6.38
AstraZeneca PLC 4.15
Eli Lilly & Co 3.53
Sanofi 2.88
Abbott Laboratories 2.84
Merck & Co Inc 2.68
Novo Nordisk A/S 2.57
AbbVie Inc 2.50
Thermo Fisher Scientific Inc 2.41
Novartis AG (ADR) 2.31
Vertex Pharmaceuticals Inc 2.29
Sarepta Therapeutics Inc 2.25
Boston Scientific Corp 2.22
Danaher Corp 2.14
Roche Holding AG 1.94
Argenx SE (ADR) 1.87
Elevance Health Inc 1.69
Stryker Corp 1.61
ImmunoGen Inc 1.36
AmerisourceBergen Corp 1.33
Humana Inc 1.30
HCA Healthcare Inc 1.21
Illumina Inc 1.18
Madrigal Pharmaceuticals Inc 1.13
Vaxcyte Inc 1.12
Zoetis Inc 1.10
Ascendis Pharma A/S (ADR) 1.09
Centene Corp 1.03
BioMarin Pharmaceutical Inc 1.03
Akero Therapeutics Inc 1.03
Amgen Inc 1.02
Intuitive Surgical Inc 1.00
United Therapeutics Corp 1.00
Cooper Cos Inc 1.00
Medtronic PLC 0.99
Bristol-Myers Squibb Co 0.96
Edwards Lifesciences Corp 0.95
DexCom Inc 0.94
Neurocrine Biosciences Inc 0.94
PTC Therapeutics Inc 0.93
Johnson & Johnson 0.90
Globus Medical Inc 0.89
Astellas Pharma Inc 0.86
Bayer AG 0.85
STERIS PLC 0.80
Legend Biotech Corp (ADR) 0.79
Zai Lab Ltd (ADR) 0.78
Pfizer Inc 0.77
Amicus Therapeutics Inc 0.74
Avadel Pharmaceuticals PLC (ADR) 0.73
Baxter International Inc 0.73
Teleflex Inc 0.71
Prothena Corp PLC 0.68
Penumbra Inc 0.65
Royalty Pharma plc 0.61
Biohaven Ltd 0.57
Travere Therapeutics Inc 0.57
Align Technology Inc 0.56
Catalent Inc 0.55
Cytokinetics Inc 0.54
Gilead Sciences Inc 0.51
DENTSPLY SIRONA Inc 0.50
IQVIA Holdings Inc 0.50
Tandem Diabetes Care Inc 0.49
Organon & Co 0.48
NeoGenomics Inc 0.46
Alnylam Pharmaceuticals Inc 0.46
Cymabay Therapeutics Inc 0.45
Takeda Pharmaceutical Co Ltd 0.45
Regeneron Pharmaceuticals Inc 0.45
Ventyx Biosciences Inc 0.44
Ardelyx Inc 0.40
Biomea Fusion Inc 0.39
New Horizon Health Ltd 0.36
Arcellx Inc 0.35
4D Molecular Therapeutics Inc 0.34
ICON PLC 0.32
Roivant Sciences Ltd 0.32
89bio Inc 0.31
Insmed Inc 0.30
Moderna Inc 0.28
REVOLUTION Medicines Inc 0.27
ICU Medical Inc 0.26
Reata Pharmaceuticals Inc 0.25
ACELYRIN Inc 0.23
Privia Health Group Inc 0.21
Bicycle Therapeutics PLC (ADR) 0.21
Intra-Cellular Therapies Inc 0.20
Cerevel Therapeutics Holdings Inc 0.20
Collegium Pharmaceutical Inc 0.20
Ideaya Biosciences Inc 0.19
Rhythm Pharmaceuticals Inc 0.18
Seres Therapeutics Inc 0.17
Janux Therapeutics Inc 0.17
Element Biosciences Inc 0.14
Bigfoot Biomedical Inc 0.14
Shoreline Biosciences Inc 0.12
Disc Medicine Inc/old 0.12
Synthekine Inc 0.12
Heartflow Inc 0.11
Curevo Inc 0.11
Freenome Holdings Inc 0.08
Freenome Holdings Inc 0.08
Lexeo Therapeutics Inc 0.08
Sonoma Biotherapeutics Inc 0.08
Attralus Inc 0.07
Design Therapeutics Inc 0.07
Magnolia Medical Technologies Inc 0.06
Arbor Biotechnologies Inc 0.05
Neurogene Inc 0.05
Hemoshear Therapeutics LLC 0.04
Neurogene Inc 0.04
Sonoma Biotherapeutics Inc 0.04
Asher Biotherapeutics Inc 0.04
Twinstrand Biosciences Inc 0.03
DICE Therapeutics Inc 0.03
Bigfoot Biomedical Inc 0.02
Leap Therapeutics Inc 0.02
Lexeo Therapeutics Inc 0.02
ACELYRIN INC 0.01
Canbridge Pharmaceuticals Inc 0.01
Leap Therapeutics Inc 0.00
Leap Therapeutics Inc 0.00
Clementia Pharmaceuticals Inc 0.00
SomaLogic Operating Co Inc 0.00
Cash & Equivalents 0.74
Janus Henderson publishes this listing of securities held as of the most recently available disclosure period, which varies depending on the portfolio. Any portion of holdings may be excluded from publication when deemed in the best interest of the portfolio. Securities are reported at market value.
The portfolio data and its presentation here is based on the investment book of record and may differ from the accounting book of record and complete schedules of investments in regulatory filings due to differing accounting and reporting standards.