For Financial Professionals in the US

Global Life Sciences Fund Holdings

Full Portfolio Holdings

(As of 09/30/2020)

% OF INVESTMENTS
Merck & Co Inc 3.70
UnitedHealth Group Inc 3.51
Novartis AG (ADR) 3.35
Thermo Fisher Scientific Inc 3.11
Roche Holding AG 3.05
AbbVie Inc 3.01
AstraZeneca PLC 2.99
Abbott Laboratories 2.60
Humana Inc 2.57
Boston Scientific Corp 2.42
Bristol-Myers Squibb Co 2.29
Sanofi 2.21
Eli Lilly and Co 1.98
Danaher Corp 1.95
Medtronic PLC 1.79
Neurocrine Biosciences Inc 1.73
Horizon Therapeutics Plc 1.69
Johnson & Johnson 1.60
Vertex Pharmaceuticals Inc 1.60
Elanco Animal Health Inc 1.57
Ascendis Pharma A/S (ADR) 1.53
Sarepta Therapeutics Inc 1.47
Centene Corp 1.31
IQVIA Holdings Inc 1.29
Gilead Sciences Inc 1.27
Catalent Inc 1.22
Alexion Pharmaceuticals Inc 1.20
BioMarin Pharmaceutical Inc 1.16
Royalty Pharma Finance Trust 1.16
Novo Nordisk A/S 1.15
ACADIA Pharmaceuticals Inc 1.11
Anthem Inc 1.09
Insmed Inc 1.08
Mirati Therapeutics Inc 1.07
Jazz Pharmaceuticals PLC 1.05
Takeda Pharmaceutical Co Ltd 0.95
GW Pharmaceuticals PLC (ADR) 0.93
Global Blood Therapeutics Inc 0.93
Baxter International Inc 0.91
Acceleron Pharma Inc 0.90
Amicus Therapeutics Inc 0.83
Intuitive Surgical Inc 0.82
Cooper Cos Inc 0.80
Sage Therapeutics Inc 0.80
Edwards Lifesciences Corp 0.78
Akero Therapeutics Inc 0.73
Stryker Corp 0.71
Quest Diagnostics Inc 0.70
STERIS PLC 0.69
Globus Medical Inc 0.68
Align Technology Inc 0.67
ICU Medical Inc 0.65
Rhythm Pharmaceuticals Inc 0.63
Argenx SE (ADR) 0.58
Silk Road Medical Inc 0.57
PTC Therapeutics Inc 0.56
IGM Biosciences Inc 0.56
Regeneron Pharmaceuticals Inc 0.56
DENTSPLY SIRONA Inc 0.55
Exelixis Inc 0.53
Forma Therapeutics Holdings Inc 0.53
Fate Therapeutics Inc 0.52
Astellas Pharma Inc 0.50
Teleflex Inc 0.49
Lonza Group AG 0.49
Retrophin Inc 0.48
DexCom Inc 0.47
Collegium Pharmaceutical Inc 0.46
NeoGenomics Inc 0.46
Vaxcyte Inc 0.43
iTeos Therapeutics SA 0.42
ALX Oncology Inc 0.42
Health Catalyst Inc 0.42
Acerta Project Management Co 0.41
Phathom Pharmaceuticals Inc 0.41
Illumina Inc 0.40
Bristol-Myers Squibb Co 0.38
Bridgebio Pharma Inc 0.38
FibroGen Inc 0.36
Seres Therapeutics Inc 0.36
Myovant Sciences Ltd 0.34
Axsome Therapeutics Inc 0.33
Annexon Inc 0.29
Odonate Therapeutics Inc 0.29
Olema Pharmaceuticals Inc 0.28
Ironwood Pharmaceuticals Inc 0.28
Ping An Healthcare and Technology Co Ltd 0.27
Harmony Biosciences Holdings Inc 0.26
BioNTech SE (ADR) 0.25
Vaxcyte Inc 0.25
Everest Medicines Ltd 0.24
Annexon Inc 0.23
Bigfoot Biomedical Inc 0.22
Kymera Therapeutics LLC 0.22
iTeos Therapeutics Inc 0.20
Aprea Therapeutics Inc 0.19
Kiniksa Pharmaceuticals Ltd 0.19
Dyne Therapeutics Inc 0.18
4d Molecular Therapeutics LLC 0.15
Takeda Pharmaceutical Co Ltd 0.14
Flame Biosciences Inc 0.14
ALX Oncology Holdings Inc 0.13
C4 Therapeutics Inc 0.11
VelosBio Inc 0.11
Cardiff Oncology Inc 0.10
Olema Pharmaceuticals Inc 0.10
Aligos Therapeutics Inc 0.09
BioAtla LLC 0.06
Kinnate Biopharma Inc 0.06
Freenome Inc 0.05
Aligos Therapeutics Inc 0.04
Bigfoot Biomedical Inc 0.04
Clementia Pharmaceuticals Inc 0.00
Cash & Equivalents 0.48
Please consider the charges, risks, expenses and investment objectives carefully before investing. Please see a prospectus or, if available, a summary prospectus containing this and other information. Read it carefully before you invest or send money.
Holdings are subject to change without notice.

Janus Henderson publishes this listing of securities held as of the most recently available disclosure period, which varies depending on the portfolio. Any portion of holdings may be excluded from publication when deemed in the best interest of the portfolio.

 

Securities are reported at market value.

The portfolio data and its presentation here may differ from the complete schedules of investments in regulatory filings due to differing accounting and reporting requirements.
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