What are agency mortgage-backed securities (agency MBS)?
Mortgage-backed securities are collections of residential mortgages with similar characteristics that are packaged together, or securitized, and sold to investors. The cash flows (principal and interest payments) from the underlying mortgage loans are passed through to investors.
Agency MBS are issued or guaranteed by one of three government or quasi-government agencies: Fannie Mae, Freddie Mac, and Ginnie Mae. Because of this government support, the credit risk within agency MBS is considered similar to U.S. Treasuries.
Understanding agency MBS
Explore the fundamentals of Agency MBS with our comprehensive primer. Plus, discover the potential role of MBS in investment portfolios in our exclusive video with Portfolio Manager Thomas Polus.

Key characteristics of agency MBS
Strong credit rating
Due to their government guarantee, all agency MBS carry the U.S. government’s AA+ credit rating. Therefore, the risk of principal loss is negligible.
Improved absolute returns versus U.S. Treasuries
On an absolute basis, agency MBS have outperformed U.S. Treasury bonds over longer investment horizons due to their earning an additional yield, or spread, over Treasuries.
Defensiveness
In times of market stress, higher-rated, long-duration bonds such as agency MBS tend to outperform as investors seek safety. In fact, agency MBS was one of the best-performing asset classes during the Global Financial Crisis, with the Bloomberg U.S. MBS Index recording annual returns of +6.9%, +8.4%, and +5.9% in 2007, 2008, and 2009, respectively.
Low correlation to equities
MBS have historically exhibited very low correlation to equities, making them a good diversifier for multi-asset portfolios.
Diversification of risk exposures
While government and corporate bonds expose investors to a single borrower, agency MBS are made up of millions of individual mortgages, providing investors a high degree of borrower diversification.
Risk considerations for agency MBS
The uncertainty about when, or if, a borrower will prepay a mortgage is known as prepayment risk. Prepayment risk is the primary fundamental risk for agency MBS, as borrowers may pay off or refinance their mortgage at any point, which would negate the future income on that mortgage. MBS pay an additional yield, or spread, above the yield on a comparable U.S. Treasury to compensate investors for this risk.
Other risks affecting agency MBS include sensitivity to changes in interest rates, sensitivity to interest rate volatility, and changes in supply and demand.
Why Janus Henderson for MBS?
Expertise and leadership: We believe much of the value in active bond asset management comes from security selection. Characteristics of individual securities can vary widely, and it is the role of the asset manager – ideally armed with decades of experience and sophisticated analytic systems – to pick securities that offer better risk-reward potential and combine them into a portfolio with the yield and risk targets investors seek.
We offer access to the growing and complex securitized market through our single-sector and full-coverage products.
$64.5B
Firmwide securitized assets under management
Source: Janus Henderson Investors, as of December 31, 2025.
Note: Firmwide assets include securitized products available outside of the U.S. and securitized portions of other fixed income strategies.
Dedicated MBS expertise
Global Head of Securitised Products | Portfolio Manager
Head of Structured and Quantitative Fixed Income | Portfolio Manager
Portfolio Manager | Securitised Analyst