For Financial Professionals in the US

JFNIX Global Life Sciences Fund

The fund/portfolio seeks to harness the rapid innovation in health care to generate returns by investing in companies addressing unmet medical needs or those that seek to make the health care system more efficient.

NAV
$67.15
As of 02/03/2023

1-Day Change
-$0.31 (-0.46%)
As of 02/03/2023

YTD Return
-0.27%
As of 02/03/2023

Morningstar Rating

As of 12/31/2022

Overview

ABOUT THIS FUND

The fund seeks to harness the rapid innovation in health care to generate returns by investing in companies addressing unmet medical needs or those that seek to make the health care system more efficient.

WHY INVEST IN THIS FUND

Health Care Expertise: Our domain experts have 95+ years of combined experience investing in the complex and dynamic health care sector. Our team of specialists, which include multiple Ph.D.’s, seek to understand both the science and the business of prospective investments.

Balanced Approach: We diversify the portfolio across market capitalizations, geographies and the primary sub-sectors of health care, including investments in biotechnology, health care services, medical devices and pharmaceuticals.

Integrated Risk Management Process: Security-level “Value at Risk” framework focuses attention on downside risks by limiting the position size of higher-risk stocks.

PORTFOLIO MANAGEMENT

Andy Acker, CFA

Global Life Sciences | Portfolio Manager

Industry since 1996. Joined Firm in 1999.

Daniel Lyons, PhD, CFA

Portfolio Manager | Research Analyst

Industry since 2000. Joined Firm in 2000.

Performance

RETURNS (%) (As of 12/31/2022)
Global Life Sciences Fund - Class I Shares MSCI World Health Care Index S&P 500® Index
 
3M YTD 1YR 3YR 5YR 10YR Since Inception
(12/31/1998)
Global Life Sciences Fund - Class I Shares 14.08 -2.65 -2.65 9.33 12.02 15.79 11.50
MSCI World Health Care Index 13.14 -5.41 -5.41 8.76 10.20 12.02 6.85
S&P 500® Index 7.56 -18.11 -18.11 7.66 9.42 12.56 6.84
RETURNS (%) (As of 01/31/2023)
Global Life Sciences Fund - Class I Shares MSCI World Health Care Index S&P 500® Index
 
3M YTD 1YR 3YR 5YR 10YR Since Inception
(12/31/1998)
Global Life Sciences Fund - Class I Shares 5.60 0.49 7.55 10.55 10.43 15.00 11.48
MSCI World Health Care Index 3.69 -0.65 1.47 9.04 8.86 11.18 6.79
S&P 500® Index 5.76 6.28 -8.22 9.88 9.54 12.68 7.09
Calendar Year Returns (%)
Global Life Sciences Fund - Class I Shares MSCI World Health Care Index
2022 2021 2020 2019 2018 2017 2016 2015 2014 2013
Global Life Sciences Fund - Class I Shares -2.65 6.86 25.60 29.28 4.41 22.66 -12.27 8.42 34.93 55.97
MSCI World Health Care Index -5.41 19.80 13.52 23.24 2.51 19.80 -6.81 6.60 18.10 36.27

MORNINGSTAR PERCENTILE

(As Of 12/31/2022)
1 YR 3 YR 5 YR 10 YR SINCE INCEPTION
Percentile Ranking 15 20 8 5 13
Health Category|Rank/Count 23/176 33/153 7/135 6/126 5/57
(As Of 12/31/2022)
1 YR 3 YR 5 YR 10 YR SINCE INCEPTION
Percentile Ranking 15 20 8 5 13
Health Category|Rank/Count 23/176 33/153 7/135 6/126 5/57
GROWTH OF A HYPOTHETICAL INVESTMENT

RETURNS-BASED STATISTICS (As of 12/31/2022 Class I Shares)

RISK / REWARD
VS. MSCI World Health Care Index
3YR 5YR
Information Ratio 0.08 0.27
Alpha 1.04 1.72
Tracking Error 6.98 6.79
Beta 0.96 1.02
R-squared (%) 83.63 84.08
UP/DOWN MARKET CAPTURE (%)
VS. MSCI World Health Care Index
3YR 5YR
Up Capture Ratio 89.50 103.96
Down Capture Ratio 85.43 96.35
STANDARD DEVIATION 3YR 5YR
Global Life Sciences Fund 17.17 17.00
MSCI World Health Care Index 16.35 15.29
SHARPE RATIO 3YR 5YR
Global Life Sciences Fund 0.50 0.63
MSCI World Health Care Index 0.49 0.59
ANNUAL FEES & EXPENSES (As of Fiscal Year End, 09/30/2022)
CLASS I SHARES
Management Fees 0.64%
Other Expenses 0.12%
Total Gross Expenses 0.76%
Total Net Expenses 0.76%

Portfolio

Index represents the MSCI World Health Care Index.

Top Holdings (As of 12/31/2022)
% of Fund
UnitedHealth Group Inc 6.57
AstraZeneca PLC 4.40
AbbVie Inc 3.91
Merck & Co Inc 3.00
Eli Lilly & Co 2.99
Novartis AG (ADR) 2.70
Sarepta Therapeutics Inc 2.61
Sanofi 2.60
Abbott Laboratories 2.34
Thermo Fisher Scientific Inc 2.33
Total 33.45
View full holdings
Portfolio Characteristics (As of 12/31/2022)
  FUND INDEX
Number of Holdings
Equity Issues
124 139
Market Capitalization
Weighted Average
$133.66B $181.90B
Portfolio Turnover Rate
(1-year trailing)
27.33% -
Price/Earnings Ratio
(1-year forward)
17.04 17.56
Price/Book Ratio
4.54 4.29
Earnings Growth Rate
(1-year forward)
9.07% 4.02%
Sector Allocation % OF FUND % of Index % OF FUND % of Index (As of 12/31/2022)
Regional Allocation % OF FUND % of Index % OF FUND % of Index (As of 12/31/2022)
Market Capitalization Range of Equity Holdings % OF FUND % of Index % OF FUND % of Index (As of 12/31/2022)
Developed vs Emerging Markets % OF FUND % of Index % OF FUND % of Index (As of 12/31/2022)

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