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For Financial Professionals in the US

JFNIX Global Life Sciences Fund

The fund/portfolio seeks to harness the rapid innovation in health care to generate returns by investing in companies addressing unmet medical needs or those that seek to make the health care system more efficient.

NAV
$81.37
As of 09/18/2024

1-Day Change
-$0.15 (-0.18%)
 As of 09/18/2024

YTD Return
17.47%
As of 09/18/2024

Morningstar Rating

As of 08/31/2024

Morningstar Medalist Rating ™

Bronze Morningstar Analyst Rating
As of 07/31/2024

Overview

Quarterly Update

Watch the investment team recap this quarter.

(Note: Filmed in July 2024).

ABOUT THIS FUND

The fund seeks to harness the rapid innovation in health care to generate returns by investing in companies addressing unmet medical needs or those that seek to make the health care system more efficient.

WHY INVEST IN THIS FUND

Health Care Expertise: Our domain experts have 95+ years of combined experience investing in the complex and dynamic health care sector. Our team of specialists, which include multiple Ph.D.’s, seek to understand both the science and the business of prospective investments.

Balanced Approach: We diversify the portfolio across market capitalizations, geographies and the primary sub-sectors of health care, including investments in biotechnology, health care services, medical devices and pharmaceuticals.

Integrated Risk Management Process: Security-level “Value at Risk” framework focuses attention on downside risks by limiting the position size of higher-risk stocks.

PORTFOLIO MANAGEMENT

Andy Acker, CFA

Andy Acker, CFA

Portfolio Manager

Industry since 1996. Joined Firm in 1999.

Daniel Lyons, Ph.D., CFA

Daniel Lyons, Ph.D., CFA

Portfolio Manager | Research Analyst

Industry since 2000. Joined Firm in 2000.

Performance

RETURNS (%) (As of 06/30/2024)
Global Life Sciences Fund - I Shares MSCI World Health Care IndexSM S&P 500® Index
 
3M YTD 1YR 3YR 5YR 10YR Since Inception
(12/31/1998)
Global Life Sciences Fund - I Shares 1.95 10.68 15.17 5.90 11.55 11.24 11.55
MSCI World Health Care IndexSM 0.48 7.99 11.17 4.92 10.10 8.73 6.91
S&P 500® Index 4.28 15.29 24.56 10.01 15.04 12.86 8.01
Returns quoted are past performance and do not guarantee future results; current performance may be lower or higher. Investment returns and principal value will vary; there may be a gain or loss when shares are sold.
Performance for Class I Shares that includes periods prior to 7/6/09 reflects the performance of one or more share classes of the Fund or a predecessor fund, adjusted, where applicable and permitted, for differing fees and expenses. See the Fund’s prospectus for further details.

Returns include reinvestment of dividends and capital gains. Returns greater than one year are annualized.

RETURNS (%) (As of 08/31/2024)
Global Life Sciences Fund - I Shares MSCI World Health Care IndexSM S&P 500® Index
 
3M YTD 1YR 3YR 5YR 10YR Since Inception
(12/31/1998)
Global Life Sciences Fund - I Shares 11.47 19.52 24.83 7.45 14.08 11.23 11.80
MSCI World Health Care IndexSM 11.00 17.64 20.50 5.69 12.26 9.34 7.22
S&P 500® Index 7.39 19.53 27.14 9.38 15.91 12.98 8.11
Returns quoted are past performance and do not guarantee future results; current performance may be lower or higher. Investment returns and principal value will vary; there may be a gain or loss when shares are sold.
Performance for Class I Shares that includes periods prior to 7/6/09 reflects the performance of one or more share classes of the Fund or a predecessor fund, adjusted, where applicable and permitted, for differing fees and expenses. See the Fund’s prospectus for further details.

Returns include reinvestment of dividends and capital gains. Returns greater than one year are annualized.

Calendar Year Returns (%)
Global Life Sciences Fund - I Shares MSCI World Health Care IndexSM
2023 2022 2021 2020 2019 2018 2017 2016 2015 2014
Global Life Sciences Fund - I Shares 7.54 -2.65 6.86 25.60 29.28 4.41 22.66 -12.27 8.42 34.93
MSCI World Health Care IndexSM 3.76 -5.41 19.80 13.52 23.24 2.51 19.80 -6.81 6.60 18.10
Calendar Year Returns (%)
Year I USD (Net) MSCI World Health Care NR Index US Fund Health
2023 7.54 3.76
2022 -2.65 -5.41
2021 6.86 19.80
2020 25.60 13.52
2019 29.28 23.24
2018 4.41 2.51
2017 22.66 19.80
2016 -12.27 -6.81
2015 8.42 6.60
2014 34.93 18.10
2013 55.97 36.27
2012 24.84 17.54
2011 7.30 9.46
2010 8.30 2.41
2009 26.42 18.89
2008 -28.77 -21.50
2007 22.53 3.94
2006 -1.95 10.47
2005 11.45 9.00
2004 14.95 6.00
2003 27.44 19.50
2002 -30.11 -17.98
2001 -18.09 -13.24
2000 33.34 26.63
1999 from 12/31/1998 61.00 -10.33

MORNINGSTAR PERCENTILE

(As Of 06/30/2024)
1 YR 3 YR 5 YR 10 YR SINCE INCEPTION
Percentile Ranking 12 5 5 6 8
Health | Rank/Count 32/176 11/161 14/140 10/126 5/56
(As Of 08/31/2024)
1 YR 3 YR 5 YR 10 YR SINCE INCEPTION
Percentile Ranking 17 5 4 11 11
Health | Rank / Count 36/175 13/159 13/148 14/126 5/56

GROWTH OF A HYPOTHETICAL INVESTMENT

Global Life Sciences Fund - I Shares MSCI World Health Care IndexSM Health
Source: Morningstar, Inc.
This graph compares the performance of a hypothetical $1 investment in the fund, the fund’s Morningstar category average and its benchmark(s).

RETURNS-BASED STATISTICS (As of 08/31/2024 Class I Shares)

RISK / REWARD
VS. MSCI World Health Care NR Index		 3YR 5YR
Information Ratio 0.32 0.26
Alpha 1.76 1.71
Tracking Error 5.21 6.29
Beta 1.03 1.01
R-squared (%) 89.67 84.58
UP/DOWN MARKET CAPTURE (%)
VS. MSCI World Health Care NR Index		 3YR 5YR
Up Capture Ratio 107.53 102.75
Down Capture Ratio 99.30 94.88
STANDARD DEVIATION 3YR 5YR
Global Life Sciences Fund 15.79 15.97
MSCI World Health Care NR Index 14.48 14.47
SHARPE RATIO 3YR 5YR
Global Life Sciences Fund 0.24 0.72
MSCI World Health Care NR Index 0.14 0.67
ANNUAL FEES & EXPENSES (As of the most recent prospectus)
CLASS I SHARES
Management Fees 0.64%
Other Expenses 0.13%
Total Gross Expenses 0.77%
Total Net Expenses 0.77%

Portfolio

Index represents the MSCI World Health Care Index.

Top Holdings (As of 08/31/2024)
% of Fund
Eli Lilly & Co 8.93
UnitedHealth Group Inc 6.73
Novo Nordisk A/S 5.34
AstraZeneca PLC 4.01
AbbVie Inc 3.62
Amgen Inc 3.21
Merck & Co Inc 2.80
Sanofi SA 2.63
Boston Scientific Corp 2.46
Novartis AG (ADR) 2.35
TOTAL 42.08
View full holdings
Portfolio Characteristics (As of 08/31/2024)
  FUND INDEX
Number of Holdings
Equity Issues		 110 135
Market Capitalization
Weighted Average		 $227.34B $253.64B
Portfolio Turnover Rate
(1-year trailing)		 31.48% -
Price/Earnings Ratio
(1-year forward)		 21.49 19.58
Price/Book Ratio
 5.77 4.80
Earnings Growth Rate
(1-year forward)		 23.45% 19.83%
Sector Allocation % of Fund % of Index % of Fund % of Index As of 08/31/2024
Regional Allocation % of Fund % of Index % of Fund % of Index As of 08/31/2024
Developed vs Emerging Markets % of Fund % of Index % of Fund % of Index As of 08/31/2024
Market Capitalization Range of Equity Holdings % of Fund % of Index % of Fund % of Index As of 08/31/2024

Documents

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Our intellectual capital is readily available and central to our Knowledge Shared approach"
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